Franciso de Trujillo was the only son of Diego de Trujillo and Catalina Vasquez; their other children were all daughters. Very likely Francisco married Lucía de Montoya, since she seems to be the "doña Luisa de Trujillo" whose hacienda was located in Alburquerque. ONMF p. 108. She was a daughter of Diego de Montoya and María Ortiz de Vera. (Lucía de Montoya was born about 1629).
Sources:
1) Herencia: Vol 6, Issue 2, April, 1998; Author: Quarterly Journal of the HGRC-NM; Holguin and Montes Vigil, Ancestors of John M. Garcia
2) Origins of New Mexico Families, Revised Edition 1992; Fray Angélico Chávez; Museum of NM Press.
3) HGRC-NM.org; Hispanic Genealogical Reseach Center, New Mexico; Website for Great NM Pedrigree Database; Albuquerque, NM; Electronic media.