Robert Keating was the scion of an Anglo-Irish family long established in Wexford, Ireland.
He was born in 1834 in County Wexford, Eire, came to America in 1854 and to Buffalo the next year. In Buffalo he spent eleven years with S. S. Jewett & Francis H. Root, stove manufacturers. He then formed a partnership with Jewett's son, Henry C., which, under the name Root & Jewett set up tanneries in Olean and Port Allegany, which sold out to the leather trust in 1892. Keating then moved into banking. He was a director of the Third National Bank, secretary of Standard Savings and Loan Association, and vice-president of Buffalo Savings.
In 1860 he married his then boss's daughter, Caroline W Root [1839-1866], by whom he had three children. When Caroline died in 1866, possibly in childbirth, her father, who wished an heir to perpetuate the family name, adopted Robert under the name Robert Keating Root.